Uterine NK cells and macrophages in pregnancy
نویسندگان
چکیده
منابع مشابه
Uterine NK cells and macrophages in pregnancy.
The presence of immune cells in the placental bed is important for both mother and child. Although various immune cells can be found in the placental bed, such as regulatory T cells and dendritic cells, uterine NK cells and macrophages are the most prominent immune cells in the placental bed in early pregnancy. uNK cell and macrophage numbers in the placental bed decrease in the third trimester...
متن کاملHuman uterine NK cells interact with uterine macrophages via NKG2D upon stimulation with PAMPs.
PROBLEM The initiation of an immune response often involves the cooperation of various innate immune cells. In the human endometrium, uterine natural killer (uNK) cells and uterine macrophages are present in significant numbers and in close proximity, yet how they cooperatively respond to infectious challenge is poorly understood. METHOD OF STUDY Primary autologous uNK cells and macrophages w...
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Dendritic cell (DC) and natural killer (NK) cell interactions are important for the regulation of innate and adaptive immunity, but their relevance during early pregnancy remains elusive. Using two different strategies to manipulate the frequency of NK cells and DC during gestation, we investigated their relative impact on the decidualization process and on angiogenic responses that characteriz...
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ژورنال
عنوان ژورنال: Placenta
سال: 2017
ISSN: 0143-4004
DOI: 10.1016/j.placenta.2017.03.001